Remnant 2 best weapons tier list – best guns and melee weapons to defeat Annihilation

Remnant 2 best weapons tier list – best guns and melee weapons to defeat Annihilation
Alex Raisbeck Updated on by

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With so many to choose from, it can be a struggle knowing what the Remnant 2 best weapons are. As you progress through each biome, you’ll come across some unique weapons, each with its own mods and effects. Depending on how you play, some might be incredible while some may fall flat, but there are definitely some that are top of the pile no matter what your playstyle is.

If you’re looking to upgrade your weapons but don’t have the scrap, check out our how to get scrap fast in Remnant 2 guide. And if you’re wanting to try out some new classes, find out how to unlock the Engineer archetype in Remnant 2, as well. But now, let’s take a look at the Remnant 2 best weapons to see what you should be arming yourself with on your trip through the World Crystal.

Remnant 2 best weapons: The player shooting an enemy on N'Erud.
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Remnant 2 best weapons tier list

There are plenty of weapons in Remnant 2 to choose from, and knowing which ones to use is tough. Our tier list takes into account some of the many unique weapons in the game, to let you know some of the best ones to use, as well as some that you might want to avoid. Even though some of these weapons are in the B or C tier, that doesn’t mean you shouldn’t use them, just that they’re more situational.

Here is our Remnant 2 weapons tier list:

Sorrow Handgun
Chicago Typewriter
Spectral Blade
XMG57 Bonesaw
B TierAny Standard Weapon
Cube Gun
Feral Judgement
Huntress Spear
Labyrinth Staff
Rune Pistol
C TierAtom Smasher
Red Doe Staff
A tier list of the best weapons in Remnant 2
Remnant 2 best weapons: The Nightfall inspection screen.
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Best Long Guns

The best Long Guns in Remnant 2 are:

  • Nightfall
  • Alpha-Omega
  • Chicago Typewriter / MP60-R / XMG57 Bonesaw
  • Widowmaker


On its own, Nightfall is a solid weapon, but its weapon mod, Dreadwalker, is arguably the strongest in the game. For 10 seconds, it becomes fully automatic, with infinite ammo, a 35% faster fire rate, 10% lifesteal, and it makes you harder to hit. This can shred bosses, especially if you can consistently the weak spot damage bonus from scoring critical hits, and is a must-have for any player.


Alpha-Omega is great at dealing with groups of enemies. It’s a railgun which must be charged up to fire. For every successive enemy hit, the charge time is reduced, and damage is increased by 10%, stacking up to 5x. It’s also decent against bosses, as its weapon mod, Beta Ray, inflicts a Brand on enemies, which can explode to deal heavy damage. A hugely versatile weapon.

Chicago Typewriter / XMG57 Bonesaw

These two weapons have two things in common – a large magazine, and synergy with the Hot Shot weapon mod. Available at the start of the game, activating Hot Shot with one of these weapons allows you to quickly fire dozens of flaming rounds into an enemy. Coupled with some damage boosting relics or rings, these weapons can tear through almost anything, but be careful of enemies with fire resistance. The XMG57 Bonesaw is also the starting weapon for the Medic, so something to think about when choosing your class.


The Widowmaker is a powerful sniper rifle which a massive ideal range of 35m, and is capable of dealing some incredible damage in the right hands. Bought from Brabus in Ward 13, if you can pair this with the right archetypes and the slayer mutation, you’ve got one of the most powerful guns in the game in your hands. It requires a bit more setup than most of the others on this list, but the payoff could be even higher if you can use it right and score those critical hits.

Alex’s Advice

It’s important to hit your critical hits, but even more so with the Widowmaker. The small clip and slow fire rate mean missed shots waste plenty of time, but if you can reliably hit enemy weak spots, this gun is incredibly powerful.

Remnant 2 best weapons: The Cube Gun inspection screen.

Best Handguns

The best Handguns in Remnant 2 are:

  • Sorrow Handgun
  • MP60-R
  • Cube Gun
  • Enigma

Sorrow Handgun

The Sorrow Handgun is an incredibly useful weapon thanks to its weapon mod, Eulogy. The bolts the gun fires become lodged in enemies, and when Eulogy is used, these bolts are returned to you, damaging the enemy further, while restoring your ammo and health. This is an excellent weapon if you’re wanting to save your ammo reserves through a tough biome.


This one’s great for the same reason as the Chicago Typewriter and XMG57 Bonesaw. A fast fire rate and big magazine coupled with the Hot Shot mod can shred enemies. Unlike them though, it’s a Handgun, freeing up space for a different Long Gun like the Nightfall, making it an even better choice.

Cube Gun

The Cube Gun has a five-round clip, but each shot returns to you either after hitting an enemy or surface, or when you reload. This means on large enemies, where you hit every shot, you can fire it continuously, though it can overheat. Its weapon mod also places a cube shield which absorbs damage, and can be fired forwards, unleashing the damage it blocks. You can get this from beating the Labyrinth Sentinel and bringing the Conflux Prism to McCabe.


Enigma fires an electrical current that can jump between targets. Enigma’s weapon mod, Chaos Driver, fires electrified rods into enemies or surfaces. Multiple rods will chain electricity between them, letting you create an area of electricity that deals shock damage to any enemies within it. This is a great weapon for crowd control, taking out big groups of enemies simultaneously. You can craft Enigma at McCabe by bringing her the Cipher Rod from The Labyrinth.

Remnant 2 best weapons: The Spectral Blade inspect screen.
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Best melee weapons

The best melee weapons in Remnant 2 are:

  • Spectral Blade
  • Labyrinth Staff
  • Dreamcatcher

Spectral Blade

The Spectral Blade is potentially the best melee weapon in the game thanks to its weapon mod, Whirlwind. This lets you charge up an attack which unleashes a series of slashes which damage enemies within 8m. This lets you cover huge distances while also hitting multiple enemies at once and is a great choice for your melee slot.

Labyrinth Staff

The Labyrinth Staff has no weapon mod, but its default perk makes up for that. Its basic attacks generate 10% more mod power, while its charge attacks generate 50% more. Its charge attacks also perform an AoE strike which hits all enemies within 2m. This one is great, not for its damage, but for how quickly you can build up mod power, especially if you use rings that boost that even further.


Dreamcatcher is another melee weapon with an excellent weapon mod. With the Dreamwave mod, when you use a charge attack, a Dreamwave will be released, affecting enemies within 20m. This applies slow for 10 seconds and grants you a stack of Reverie, which gives +2% boosts to damage and movement speed for 15 seconds. If used right, the Dreamcatcher can net you some incredible stat buffs against groups of enemies.

Every weapon in the game has its uses, and used correctly, some guns that would otherwise be seen as bad can be on par with some of the best in the game. However, there are some weapons that are simply head and shoulders above the rest, and those are the ones we want to talk about. That doesn’t mean you should always use these over any others, though, so take it with a pinch of salt.

That’s everything you need to know about the Remnant 2 best weapons. Naturally, use what weapons you like best, but be sure to try some of these ones out. If you’re looking for the Remnant 2 best class, we’ve got a guide for that. And if you’re starting a new playthrough and want to get to level 10 quickly, our how to level up fast in Remnant 2 guide should help you out.

What are the best weapon mods in Remnant 2?

The best weapon mods in Remnant 2 are Dreadwalker on Nightfall, and Hot Shot on weapons like the Chicago Typewriter and MP60-R.

What are the best mutators in Remnant 2?

The best mutators in Remnant 2 are Battery, Slayer, and Momentum.