Takeuchi felt 'extreme pressure'.
It was a game that divided as many fans as it pleased.
Resident Evil 5, produced by Capcom's Jun Takeuchi, won plaudits for its stunning graphics and over the top action. Indeed we loved it.
But for many long-running fans of the series it took a step too far away from the franchises' survival horror roots. And moving and shooting was impossible.
As all eyes look towards Resident Evil 6, Takeuchi has spoken out on the pressure he felt when producing last year's blockbuster and revealed that he's now had enough of the zombie action shooter series.
Speaking in an interview with Xbox World 360 magazine, Takeuchi admitted he felt "extreme pressure" working in the shadow of acclaimed Resident Evil 4 creator Shinji Mikami, who left the company in 2007.
"Yes, it's true we did feel extreme pressure - and Mikami-san's shadow - after Resi. However, because we were creating the sequel to this huge franchise we wanted to make our fresh direction clear."
He added: "Personally, I don't think I'm gonna deal with Resident Evil 6 at all - as far as the series is concerned I'm not planning to return until at least two more Olympics have passed!"
Takeuchi also produced the co-op shooter Lost Planet 2, out on May 11. To see what we thought of that, check out our review.
What do you think? Are you happy to see Jun Takeuchi and Resident Evil part ways? Let us know in the comments section below.